New PDF release: Angiotensin and the Heart

By Gerd Heusch,H. Grobecker,B.E. Strauer

ISBN-10: 0387914323

ISBN-13: 9780387914329

ISBN-10: 3798509360

ISBN-13: 9783798509368

within the final decade, ACE inhibitors became a cornerstone of cardiovascular drug remedy. useful results in sufferers with high blood pressure, center failure, and publish myocardial infarction were validated in huge medical trials. In parallel, ex perimental examine has shifted the curiosity from the instant homeostatic functionality of the circulating renin-angiotensin-system to the a number of paracrine services of neighborhood tissue renin-angiotensin-systems, together with hypertrophy, hyperplasia, athe- oenesis, and vasomotion. . It used to be the purpose or a symposium held in Hamburg, October 22-24, 1992, to assemble a world panel of experimental and scientific scientists and to debate the newest findings at the position of angiotensin and linked mediators in motor vehicle diovascular version and ailment, with a specific emphasis at the therapy of such illness via ACE inhibitors. The assembly and this ebook have been generously supported via Astra chemical substances. H. Grobecker G. Heusch B. E. Strauer Contents Foreword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V advent neighborhood expression and pathophysiological function of renin-angiotensin within the blood vessels and middle Dzau, V. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Myocardial Perfusion Angiotensin, ACE-inhibitors and endothelial regulate of vasomotor tone Luscher, T. F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 neighborhood and neurohumoral regulate of coronary blood circulate Krajcar, M., G. Heusch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 ACE-inhibitors in coronary artery ailment? Vogt, M., W. Matz, B. E. Strauer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . forty three Myocardial Hypertrophy Molecular mechanisms of cardiac gene expression Nadal-Ginard, B., V. Mahdavi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . sixty five Myocardial perfusion established and self sustaining mechanisms of neighborhood myocardial disorder in hypertrophy Vatner, S. F., L. Hittinger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Angiotensin and the Heart by Gerd Heusch,H. Grobecker,B.E. Strauer


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